Description
Summary:
Lead the development, optimization, and maintenance of computational pipelines for next-generation sequencing (NGS) data analysis in support of clinical and preclinical studies.
Highlights:
1. Lead computational pipeline development for NGS data analysis
2. Collaborate on sequencing-based assay integration into workflows
3. Design and implement scalable bioinformatics tools
For a CRO (Frontage Laboratories, Inc. – Deerfield Beach, FL): lead the development, optimization and maintenance of computational pipelines for the analysis of next-generation sequencing (NGS) data in support of clinical and preclinical studies; collaborate with multidisciplinary teams to integrate sequencing-based assays including tumor profiling, germline analysis and cell-free DNA applications into routine workflows; design and implement scalable and reproducible bioinformatics tools using R, Python, and industry-standard platforms; partner with wet lab scientists to troubleshoot and refine high-throughput genomic workflows and ensure robust assay performance across diverse biological matrices; support validation and deployment of NGS-based assays into regulated production environments; provide scientific and strategic leadership on project design, data interpretation, and regulatory documentation for client-sponsored studies.
Requirements:
Master of Science or foreign equivalent degree in Biology, Computational Biology, Genomics or a related field.
3 years of experience in the job offered or 3 years of experience as a Computational Biologist. Experience must include genomic data interpretation, tumor profiling, germline variation, cell-free DNA and integration with qPCR or proteomic data, cloud-based computing (AWS, GCP), containerization (Docker/Singularity), and version control (Git) for scalable, reproducible workflows.
Proficiency in Python, R and shell scripting.
Experience using workflow engines (e.g., Nextflow, Snakemake, WDL/Cromwell).
Knowledge of regulatory frameworks (CLIA, CAP, GLP) and assay validation processes in support of client-facing or clinical studies.
Work Location: Deerfield Beach, FL.
Hours: 40 per week - Monday through Friday.
To apply visit: https://www.frontagelab.com/about/careers/