Browse
···
Log in / Register

Principal Scientist, Drug Product Development

Negotiable Salary

Foghorn Therapeutics

Cambridge, MA, USA

Favourites
Share

Description

Our Culture: Why work with us? At Foghorn Therapeutics, we believe in “People First, Mission Always.” We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics – demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees – validated by our actions that let our people know that we care about them, their families, and their lives. We say “Mission Always” because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer. Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop. Our Science: The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people. Our proprietary Gene Traffic Control® platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way. Job Summary Foghorn Therapeutics is seeking a motivated Principal Scientist to join the drug product development group within Chemistry Manufacturing and Controls (CMC) to pursue an exciting role in cutting-edge formulation development and drug delivery technologies to support our portfolio. The individual will be responsible to take a leadership role in development of specialty drug delivery technologies and will be responsible to lead and execute the assessments of various innovative drug delivery technologies for development of complex injectables and solid oral dosage forms to support Foghorn’s portfolio at both preclinical and clinical stages. Based on experience level, the candidate will lead the CMC laboratory activities in-house and/ or also represent their function in program/ project teams allowing opportunities for cross-functional involvement/ collaboration. The candidate will also eventually support clinical formulation development and manufacture at CDMOs and regulatory filings. Requirements Requirements Minimum Qualifications PhD in chemical engineering, pharmaceutics, chemistry, material science or related field 5+ years of industry experience in drug delivery areas or formulation/drug delivery experience in the pharmaceutical industry for Sr. Scientist. Experience in LAI (long-acting injectables) Preferred Qualifications and Role Expectations Prior experience and a good understanding of one or more long acting or targeted drug delivery technologies such as nanosuspensions, liposomes, PLGA microspheres technology are preferred. Excellent scientific knowledge in formulation technologies, material science, chemistry, preformulation and formulation sciences – experience / exposure in drug delivery, complex / long acting parenterals, modified release formulation platforms are a significant plus and will be preferred Laboratory based skills including various drug delivery platforms, analytical characterization is a must. Ability to learn rapidly, have a flexible mindset and to be able to adapt to fast paced highly matrixed environments Effective verbal and written communication skills A desire to be part of a highly innovative company aimed at helping patients with serious diseases Benefits Foghorn Therapeutics is pleased to provide you and your family with a comprehensive suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options BCBS PPO and PPO HSA plans BCBS Dental Plan EyeMed Vision Plan FSA and HSA for medical expenses and dependent care expenses 401(k) Program via Fidelity with the company match Corporate Wellness Program Unlimited Paid Time Off policy Winter shut down 12 weeks of 100% paid parental leave for birthing/primary parent and primary guardian in case of adoption and 3 weeks of 100% paid parental leave for non-birthing/non-primary parent/guardian. Paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Free parking, subsidized commuter passes, or a $100 monthly stipend for walking/biking to work Company lunches on Wednesdays Foghorn Therapeutics is a smoke-free, alcohol-free and drug-free work environment. Foghorn is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Foghorn Therapeutics will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Source:  workable View original post

Location
Cambridge, MA, USA
Show map

workable

You may also like

Craigslist
Mushroom Harvest Technician – Part Time (oakland west)
Job Title: Mushroom Harvest Technician (Oakland West) Compensation: $25/ hr Employment Type: Part-time Overview We are a small medicinal mushroom company rooted in science and guided by intention. Our focus is on crafting high-integrity mushroom products that support healing, self-discovery, and joy — always with a commitment to transparency, sustainability, and natural ingredients. We’re currently hiring one part-time Mushroom Harvest Technician to join our Oakland-based team. This is hands-on work best suited to individuals with a high attention to detail, a steady hand, and a passion for natural products. You'll be working in a focused, sober, and supportive environment with a small team that values quality, a motivated pace, and attention to detail. Qualifications Experience in cannabis trimming or similar roles is preferred Comfortable working in a sober work environment Strong attention to detail and consistency in a fast-paced production setting Good hand-eye coordination and manual dexterity Able to sit or stand for extended periods and perform repetitive tasks Self-motivated and able to work independently Team-oriented with solid communication skills Comfortable working in a fast-paced production environment Responsibilities Efficiently harvest mushrooms from fruiting blocks with precision and care Gently brush and sort fresh mushrooms into bins Return resealed bags to shelves or pull them for cold storage Maintain clean workstations and follow safety protocols Assist with occasional packaging of edibles or other products as needed Work efficiently and maintain a steady pace to meet daily production goals Pay Structure Flat hourly: $25/hr for all tasks (harvesting, drying, packaging support, deep cleaning, QC, etc.). Same rate during training. Schedule Part-time: 2–4 shifts/week, typically 8 hours per shift Weekly schedule is finalized and posted by Friday for the following week based on harvest load; we communicate any changes as early as possible Shifts will include a mix of harvest-focused and lighter coverage days for quality control and upkeep Start: ASAP Physical and Mental Demands This job requires periods of standing, sitting, lifting, repetitive motion, and close visual work. Applicants should be comfortable performing physical tasks in a focused setting for multiple hours at a time. Reasonable accommodations will be made as needed. To Apply Please email the following to be considered: Your resume 2–3 references A brief description of who you are, why this role interests you, and why you believe you'd be a great fit for the position We look forward to hearing from you!
1109 Linden St, Oakland, CA 94607, USA
$25/hour
Workable
Research and Development Engineer I/II - Process Development
Cresilon® is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company’s proprietary hydrogel technology. The company’s plant-based technology has revolutionized the current standard by stopping traumatic and surgical bleeds in seconds without the need for extended manual pressure. The company's current and future product lines target veterinary, human trauma, and human surgical applications. Cresilon's mission is to save lives. Learn more about the company at www.cresilon.com. Description: The R&D Engineer I/II is responsible for supporting product design and process development activities while ensuring compliance with all quality and regulatory requirements.  The position has a scientific focus that includes implementation of formulation development through process development, prototype fabrication, and characterization, along with additional process evaluation and data generation through designed experiments.  Process development in an R&D environment will be followed by qualification and technology transfer into manufacturing.  Collaboration is a key aspect of this role, as the engineer will work within a multidisciplinary team of researchers and engineers. The position offers diverse opportunities in a collaborative cross-functional environment, requiring adaptability, flexibility, and a willingness to learn and innovate in the exploration of new technologies, new approaches, and techniques in pursuit of product/process robustness and innovation.   The R&D Engineer I/II is expected to possess expertise in areas including, but not restricted to, polymer, chemical, material science, and process development and engineering. Additionally, they will assist in generating documentation essential for regulatory submissions, ongoing publication initiatives, and direct communication with the Head of Research regarding various tasks.   This is a full-time, on-site position, located in Brooklyn, New York. This role is an independent contributor role (i.e. no direct reports). Level is dependent on experience.    Responsibilities: Oversee the planning, implementation, and analysis of experiments relevant to project objectives. Ensure the application of established scientific and engineering principles to solve complex problems and challenges innovatively and efficiently, adhering to rigorous scientific methodologies and protocols. Create and execute product/process enhancement, and new product/process development plans. Lead material/design/process changes and their implementation with well-documented research/analyses.  Process and analyze results, Author protocols and reports including engineering studies and design verification/validation activities. Aid in the development and execution of testing methods to aid in exploratory research, product/process development, and quality control; conduct chemical and mechanical property evaluation tests to assess the desirability of process or formulation changes.  Prepare samples as required for manufacturing, testing, or other evaluations and data analysis.  Participate in voice-of-customer (VOC) labs and other user needs assessments. Interface with external vendors, customers, and suppliers. Specify equipment and process requirements for developing and implementing new products, product improvement and new equipment/processes. Support process and product transfers to manufacturing or CDMOs. Maintain a laboratory notebook and other technical documentation according to required GLP/GMP guidelines. Understand and prioritize process improvements, design experiments to make those improvements, and execute these plans in the laboratory. Maintain active dialogue with Regulatory Affairs as subject matter expert on all product design elements/documentation about research towards FDA/regulated authority submissions. Provide support to the marketing and sales team, with the development of presentations, sales tools, and application data. Work with company leadership to evaluate existing research practices and contribute to a culture of ethical, high-quality research operations within the organization. Provide other project or product support as needed to support Cresilon’s business objectives. Requirements Required Qualifications Education:  BS in Chemical Engineering, Polymer Engineering, Material Science & Engineering, or related engineering discipline.  Minimum 4+ years previous experience in an industrial environment with a BS degree.  (2 years minimum experience if advanced degrees). Proficiency as an adept experimentalist with hands-on experience in the process development of polymeric materials and their characterization in an R&D or manufacturing environment. Mathematically inclined with strong analytical and problem-solving skills with the ability to be observant and to think creatively.  Demonstrated ability to design experiments and analyze data with the use of appropriate quality and statistical methodologies. Demonstrated ability to work independently as well as be a strong team contributor. Ability to effectively work within a team and cross-functionally to expedite the completion of critical project tasks. Requires understanding of product/process design and engineering. Experience should include process development/validation and/or transfer/verification, protocols, and troubleshooting skills. Ability to handle multiple project assignments of medium scope and complexity and able to prioritize and complete work with a sense of urgency on time. Ability to lead directly and by influence, including strong problem-solving, conflict resolution, and analytical skills. Working knowledge of Good Documentation Practices (GDP) and Good Manufacturing Practices (cGMP) requirements. Proficiency in the use of Microsoft Office, Microsoft Excel, Microsoft Word, Microsoft PowerPoint is required. Requires excellent written and verbal communication and presentation skills. Legal authorization to work in the United States is required. Physical Requirements include: Aseptic Gowning Qualification: Able to be successfully qualified for aseptic gowning, including successful respirator training. Wear Appropriate Personal Protective Equipment (PPE): Be able to stand and walk for prolonged periods, with the ability to climb, balance, stoop, bend, reach, and handle equipment. Ability to speak, listen, and understand verbal and written communication. Possesses hand-eye coordination and manual dexterity for delicate manipulations. Ability to lift up to 50 pounds occasionally and to carry, push, pull, or otherwise move objects. Visual acuity is required for performing close and distant activities. Preferred Qualifications An advanced technical degree (MS or PhD). ·Lab experience in an industry setting within cGMP-regulated environments. Prior experience developing processes and scaling these up into manufacturing or CDMO Mechanical/electrical knowledge with the ability to troubleshoot processing equipment Six Sigma green belt or black belt certification preferred. Experience implementing process and quality improvements in a manufacturing environment Work experience with the medical device or pharmaceutical industries Working knowledge of ISO 9001, ISO 13485:2003 and ISO 14971:200. Working knowledge of FDA requirements as per 21 CFR 820.  Cresilon is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship. Cresilon makes hiring decisions based solely on qualifications, merit, and business needs at the time. Benefits Competitive annual base salary range of $70,000 - $120,000, depending upon job level and qualifications Paid Vacation, Sick, & Holidays Monthly MetroCard Reimbursement 401(k) & Roth Retirement Savings Plan with company match up to 5% Work/Life Employee Assistance Program Company Paid Life and Short-Term Disability Coverage Medical, Dental, and Vision Insurance, FSA: Dependent & Healthcare, Commuter & Parking Benefits, Long Term Disability Coverage
Brooklyn, NY, USA
$70,000-120,000/year
Workable
Scientist
Millennium Health LLC is an accredited specialty laboratory with more than a decade of experience in medication monitoring and drug testing services, helping clinicians monitor the use and misuse of prescription medications and illicit drugs. The testing is used by healthcare professionals to obtain objective information about patients’ recent use of prescription medications and/or illicit drugs and helps monitor the effectiveness of treatment plans. A scientist who develops clinical LC-MS/MS assays.  Independently performs original scientific research and develops appropriate analytical technologies.  Manages resources and timelines for the project team. The following are intended to be examples of the accountabilities for which the person in this position is responsible.  This position is not intended to be complete or all-inclusive and does not preclude management from assigning other or related functions for which the individual has demonstrated competency through performance. Technical leader who develops, manages, and independently executes the research and development plan, to design, develop, and validate high-quality LC-MS/MS  assays/products/technologies within pre-defined timelines. Provide formal/informal scientific mentoring within the project team. Applies technical and functional knowledge to design experiments and independently complete work within own project team, working on multiple projects in parallel. Acts as a technical and scientific resource within the organization. Draft, review, and complete technical documents required for various stages of product development. Maintain detailed experiment records in lab notebooks and follow SOPs in compliance with company guidelines. Ability to ensure HIPAA, Confidentiality, and Compliance policy, procedures, and standards are always adhered to. Ability to ensure administrative, physical, and technical cybersecurity controls are always adhered to. Regular and reliable attendance. Requirements MS in Sciences such as Biology, Biochemistry, Chemistry, or a related field. PhD. preferred At least 5 years of industrial experience, preferably in an R&D analytical laboratory. Extensive hands-on experience with LC-MS techniques, including sample preparation, chromatography, method development, data interpretation, and validation. Familiarity with GLP and cGMP environment, LIMS experience, and project management. Understanding the principles of statistical tools is highly desirable Demonstrated ability and proven track record of successful development of assays/products. Excellent writing and verbal communication and presentation skills. Strong team player in a multidisciplinary environment; fully committed to development timelines. Benefits Medical, Dental, Vision, Disability Insurance  401 (k) with Company Match   Paid Time off and Holidays  Tuition Assistance  Behavioral and Health Care Resources Potential Hiring Range: Salary Range:  $115,000 – $135,000 /yr. Salary offered is dependent on qualifications, experience, and geographical location.     Millennium Health is an Equal Opportunity/Affirmative Action Employer and E-Verify participant. All qualified applicants will receive consideration for employment without regard to race, color, creed, sex, national origin, disability, gender identity, sexual orientation or protected veteran status. California Employee Privacy Notice - Millennium Health LLC https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm
San Diego, CA, USA
$115,000-135,000/year
Workable
Quantum Scientist
We are pioneering advancements in quantum computing by utilising trapped ion technology and our proprietary laser-free quantum control methods. Our research and development efforts build on our fully integrated quantum processors that can be fabricated within standard silicon foundries. This unique approach allows us to leverage the highest-performing qubit technology while ensuring scalability and manufacturability using existing semiconductor fabrication technology. We approach quantum computing with a focus on minimising errors, striving to achieve ultra-low gate errors at scale. Our immediate objective is to develop functional quantum computers within the NISQ regime, aiming to construct fault-tolerant machines that require minimal QEC overhead. Our recent breakthroughs include achieving 99.97% fidelity in two-qubit gates and 99.9992% fidelity in single-qubit operations without error correction, setting new industry standards for performance. What to expect: As a Quantum Scientist, you will be at the forefront of our research efforts, working hands-on with our current hardware while helping to shape future generations of quantum processors. Your work will span designing, debugging, and executing experiments, developing novel control schemes, and pushing the boundaries of system performance. What you’ll be responsible for:  Prototype and characterise coherent control and cooling schemes for trapped-ion qubits using laser and microwave fields. Calibrate and benchmark quantum systems, focusing on achieving ultra-low gate errors and optimising performance across device modules. Validate emerging trap technologies, including integrated electronics and photonics for large-scale architectures. Analyse experimental data, debug complex hardware/software interactions, and ensure reliability of qubit operations. Present results internally and externally, representing Oxford Ionics at conferences and in collaborations. Requirements You will need a PhD in physics or a related discipline, with a strong foundation in atomic or qubit-related physics. While prior postdoctoral or industry experience is valuable, this role is also open to candidates moving directly from a PhD. A solid background in quantum control, with hands-on experience in calibration, benchmarking, or coherent control of qubits, will be key to success. Practical skills in control software, hardware integration, or experimental data analysis are also important. You will need: Proven expertise in experimental AMO physics or quantum computing.  Experience with trapped ions is preferred. Strong collaborative skills, with the ability to work independently and as part of a fast-moving team. Prior experience in one or more of the following: spectroscopy or simulation of multi-level systems, characterisation of control hardware, gate fidelity benchmarking or running algorithms on hardware. Strong proficiency in programming and data analysis. A track record of scientific communication through publications, talks and conferences. Benefits Oxford Ionics is leading the way in quantum technology, and we need skilled, innovative individuals like you. We offer a range of benefits, including opportunities to further your career with a world-class team, business stock options, generous annual leave, flexible working, medical, dental and vision insurance for you and your family, and much more. Join us and be part of the future of quantum computing. Salary Range $125,000-$145,000 DOE Oxford Ionics is committed to equal opportunity for all.
Boulder, CO, USA
$125,000-145,000/year
Cookie
Cookie Settings
Our Apps
Download
Download on the
APP Store
Download
Get it on
Google Play
© 2025 Servanan International Pte. Ltd.