Research and Development Engineer I/II - Process Development

Trialmed Melbourne (formerly Optimal Research) is looking for overall healthy volunteers to participate in a clinical research trial to help advance vaccine research. Qualifications: • 18 to 70 years old • Health status is further evaluated by reviewing medical history, screening assessments, and visit with physician • Available and willing to commit to the trial visit structure - You will be asked to come to our clinic for 8 outpatient visits and 2 follow-up phone calls Eligible participants will receive trial related care and assessments at no cost and may be compensated up to $1,250 for trial related time. If you are interested in participating, please complete the contact form. We will follow up with more information and schedule an appointment to see if you qualify. Additional Details

Millennium Health LLC is an accredited specialty laboratory with more than a decade of experience in medication monitoring and drug testing services, helping clinicians monitor the use and misuse of prescription medications and illicit drugs. The testing is used by healthcare professionals to obtain objective information about patients’ recent use of prescription medications and/or illicit drugs and helps monitor the effectiveness of treatment plans. A scientist who develops clinical LC-MS/MS assays.  Independently performs original scientific research and develops appropriate analytical technologies.  Manages resources and timelines for the project team. The following are intended to be examples of the accountabilities for which the person in this position is responsible.  This position is not intended to be complete or all-inclusive and does not preclude management from assigning other or related functions for which the individual has demonstrated competency through performance. Technical leader who develops, manages, and independently executes the research and development plan, to design, develop, and validate high-quality LC-MS/MS  assays/products/technologies within pre-defined timelines. Provide formal/informal scientific mentoring within the project team. Applies technical and functional knowledge to design experiments and independently complete work within own project team, working on multiple projects in parallel. Acts as a technical and scientific resource within the organization. Draft, review, and complete technical documents required for various stages of product development. Maintain detailed experiment records in lab notebooks and follow SOPs in compliance with company guidelines. Ability to ensure HIPAA, Confidentiality, and Compliance policy, procedures, and standards are always adhered to. Ability to ensure administrative, physical, and technical cybersecurity controls are always adhered to. Regular and reliable attendance. Requirements MS in Sciences such as Biology, Biochemistry, Chemistry, or a related field. PhD. preferred At least 5 years of industrial experience, preferably in an R&D analytical laboratory. Extensive hands-on experience with LC-MS techniques, including sample preparation, chromatography, method development, data interpretation, and validation. Familiarity with GLP and cGMP environment, LIMS experience, and project management. Understanding the principles of statistical tools is highly desirable Demonstrated ability and proven track record of successful development of assays/products. Excellent writing and verbal communication and presentation skills. Strong team player in a multidisciplinary environment; fully committed to development timelines. Benefits Medical, Dental, Vision, Disability Insurance  401 (k) with Company Match   Paid Time off and Holidays  Tuition Assistance  Behavioral and Health Care Resources Potential Hiring Range: Salary Range:  $115,000 – $135,000 /yr. Salary offered is dependent on qualifications, experience, and geographical location.     Millennium Health is an Equal Opportunity/Affirmative Action Employer and E-Verify participant. All qualified applicants will receive consideration for employment without regard to race, color, creed, sex, national origin, disability, gender identity, sexual orientation or protected veteran status. California Employee Privacy Notice - Millennium Health LLC https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm

Our study for DIHYDROBERBERINE has been adjusted to allow for adults up to 65 years of age (previously 55)!! We have a new research study evaluating the effects of a dietary supplement on glucose and appetite response in adults. Recent clinical studies suggest berberine may impact appetite-regulating hormones like glucagon-like peptide-1 (GLP-1); insulin sensitivity (how your body responds to the insulin in your blood); blood glucose levels and weight loss. Dihydroberberine (DHB), is a form of berberine that has the same characteristics as berberine but may be better absorbed by the body. The purpose of this research study is to evaluate the effect of a single dose of DHB and 6-weeks of DHB consumption versus placebo on various health outcomes. The total study participation is approximately 8 weeks with 4 in-clinic visits. Three of the visits require you to be at the clinic for a 3-hour period. During the study, you’ll wear a continuous glucose monitor (CGM). Using a CGM requires you to wear a small sensor with a very thin filament that stays under your skin and constantly reads your blood sugar levels. If qualified, you may be compensated up to $1,000 for completing all visits and study tasks. Qualified participants must: • Be an adult between 35-65 years of age • Have a BMI ≥25 and ≤ 35 kg/m2 • Be willing to attend three 3-hour visits with an IV catheter placed in the arm for multiple blood draws • Be willing to consume 4 capsules a day for 6 weeks, specifically 2 capsules in the morning and 2 capsules in the evening • Be willing to consume a vanilla flavored meal replacement drink • Be willing to wear a continuous glucose monitor • Be willing to download smart phone applications to track blood sugar and food and beverage intake To see if you qualify, give us a call at 630-617-2000 or complete the survey below: https://biofortis.clinicalconductor.com/CCEWeb/Forms/frmSurveyPreview.aspx?Direct=1&Mode=0&SurveyPKey=250&StudyPKey=6665

We are pioneering advancements in quantum computing by utilising trapped ion technology and our proprietary laser-free quantum control methods. Our research and development efforts build on our fully integrated quantum processors that can be fabricated within standard silicon foundries. This unique approach allows us to leverage the highest-performing qubit technology while ensuring scalability and manufacturability using existing semiconductor fabrication technology. We approach quantum computing with a focus on minimising errors, striving to achieve ultra-low gate errors at scale. Our immediate objective is to develop functional quantum computers within the NISQ regime, aiming to construct fault-tolerant machines that require minimal QEC overhead. Our recent breakthroughs include achieving 99.97% fidelity in two-qubit gates and 99.9992% fidelity in single-qubit operations without error correction, setting new industry standards for performance. What to expect: As a Quantum Scientist, you will be at the forefront of our research efforts, working hands-on with our current hardware while helping to shape future generations of quantum processors. Your work will span designing, debugging, and executing experiments, developing novel control schemes, and pushing the boundaries of system performance. What you’ll be responsible for:  Prototype and characterise coherent control and cooling schemes for trapped-ion qubits using laser and microwave fields. Calibrate and benchmark quantum systems, focusing on achieving ultra-low gate errors and optimising performance across device modules. Validate emerging trap technologies, including integrated electronics and photonics for large-scale architectures. Analyse experimental data, debug complex hardware/software interactions, and ensure reliability of qubit operations. Present results internally and externally, representing Oxford Ionics at conferences and in collaborations. Requirements You will need a PhD in physics or a related discipline, with a strong foundation in atomic or qubit-related physics. While prior postdoctoral or industry experience is valuable, this role is also open to candidates moving directly from a PhD. A solid background in quantum control, with hands-on experience in calibration, benchmarking, or coherent control of qubits, will be key to success. Practical skills in control software, hardware integration, or experimental data analysis are also important. You will need: Proven expertise in experimental AMO physics or quantum computing.  Experience with trapped ions is preferred. Strong collaborative skills, with the ability to work independently and as part of a fast-moving team. Prior experience in one or more of the following: spectroscopy or simulation of multi-level systems, characterisation of control hardware, gate fidelity benchmarking or running algorithms on hardware. Strong proficiency in programming and data analysis. A track record of scientific communication through publications, talks and conferences. Benefits Oxford Ionics is leading the way in quantum technology, and we need skilled, innovative individuals like you. We offer a range of benefits, including opportunities to further your career with a world-class team, business stock options, generous annual leave, flexible working, medical, dental and vision insurance for you and your family, and much more. Join us and be part of the future of quantum computing. Salary Range $125,000-$145,000 DOE Oxford Ionics is committed to equal opportunity for all.

Join Our Clinical Trial for Active IgG4-related Disease Are you or someone you care about living with Active IgG4-related Disease? Take a step toward better health by participating in a clinical trial focused on advancing treatment options for this rare autoimmune condition. We are currently seeking volunteers to help evaluate a new investigational medication designed to target the immune system pathways involved in IgG4-RD. Study-related care and medication are provided at no cost, and participants will be compensated for their time and travel. Call (408) 443-5340 Now! Or Apply Here Why Participate? Compensation: Get compensated for up to $2,500! Comprehensive Support: Regular check-ins and assessments to ensure your health is a priority. Our trial is conducted by experienced healthcare professionals dedicated to your well-being. Study medications: Study-related medication are given at no cost. To qualify: *Must be male or female between 18 years of age or older *Clinical Diagnosis of Active IgG4-related Disease Check out our other studies! * Asthma * Chronic Low Back Pain * Refractory or Unexplained Chronic Cough * Future Studies San Jose Clinical Trials Let’s work together towards better health! Call us today at (408) 443-5340 or visit https://sanjosetrials.com/ to learn more and see if you qualify.

Cresilon® is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company’s proprietary hydrogel technology. The company’s plant-based technology has revolutionized the current standard by stopping traumatic and surgical bleeds in seconds without the need for extended manual pressure. The company's current and future product lines target veterinary, human trauma, and human surgical applications. Cresilon's mission is to save lives. Learn more about the company at www.cresilon.com. Description: The Medical Device Engineer is responsible for leading the design and development activities of new products and improving existing products in compliance with all quality and regulatory requirements. S/he will be responsible for authoring technical documents for the development of medical devices and combination products according to relevant Design Control regulations and standards. The person in this position will also be responsible for providing project-specific support, including technical analysis and review of supplier documentation as required. The position has a scientific focus that includes formulation development, product performance characterization, and implementation including proto-type design and fabrication and data generation through designed experiments. The Medical Device Engineer is expected to aspire for excellence with a bias toward action, willing to roll up their sleeves, get hands-on, and do what’s necessary to move projects forward in a fast-paced environment. They are committed to designing and developing products that dominate the marketplace and improve healthcare by partnering with our customers to drive purposeful innovation, resulting in best-in-class products. The Medical Device Engineer will work with a multidisciplinary team of researchers. This is a multi-faceted job in a highly collaborative environment across multiple functions that will require flexibility as well as an ability to learn about and develop new technologies and explore new techniques in pursuit of product innovation and robustness. Role level is contingent on experience, but this is not an entry level role.. This is a full-time, on-site position, located in Brooklyn, New York. Responsibilities Create and lead experimentation for exploratory and/or product development research focusing on polymeric materials devices and their use. Define new product functional requirements (design inputs/user needs) and evaluate the design's overall effectiveness, cost, reliability, and safety. Lead cross-functional teams to develop new products, address design issues, and maintain existing designs. Apply strong problem-solving skills to find solutions to complex problems. Work independently to plan and schedule own activities necessary to meet project timelines. Work cooperatively with, quality, manufacturing, regulatory, clinical, and marketing to ensure project success. Lead the creation of design history file documentation through the new product development process. Develop new implant and instrument designs utilizing Solidworks and modeling/detail design specifications. Generate technical protocols/reports to support device safety and efficacy. Invent/create concepts and designs and submit invention disclosures. Ensure that all design activities adhere to FDA Quality System Regulations and ISO 13485 design control and risk management requirements. Lead material/design/process changes through a design control process, with well-documented research/analyses. Author protocols and reports including development studies and design verification/validation activities. Develop and execute test methods to aid in exploratory research, product development, and quality control; conduct chemical and mechanical property evaluation tests to assess the desirability of process or formulation changes. Exercise technical judgment in the design, execution, and interpretation of experiments within the scope of project responsibilities and ensure the use of professional concepts to solve complex problems in creative and effective ways, in conformance with scientific methods and procedures. Prepare samples as required for testing, or other evaluations and data analysis, including in voice-of-customer (VOC) labs. Interface with customers, suppliers, and internal cross-functional team members to develop specifications and coordinate prototype fabrication. Maintain a laboratory notebook and other technical documentation to required GLP/GMP guidelines. Maintain active dialogue with Regulatory Affairs as subject matter expert on all product design elements/documentation pertaining to research towards FDA/regulated authority submissions, Provide support to marketing and sales team, support the introduction of new technologies with the development of presentations, sales tools, formulations, and applications data Communicate results to the scientific community via published papers. Present research at academic/industry symposia as an external representative of the company. Manage part-time staff as a research leader and mentor for ongoing research projects. Work with company leadership to evaluate existing research practices and contribute to a culture of ethical, high-quality research operations within the organization. Provide other project or product support as needed in order to support Cresilon’s business objective. Responsibilities may include other duties as assigned and as required. Requirements Required Qualifications BS in Chemical Engineering, Polymer Engineering, Material Science, Biomedical Engineering, Mechanical Engineering, or related scientific discipline. A minimum of 4+ years of product development experience is required. A minimum of 2 years of hands-on experience in new product research and development in a cGMP-regulated industry is required (work experience in the Medical Device field is strongly preferred) Adept experimentalist with hands-on experience in product development of medical devices and their safety/efficacy characterization in an R&D environment. Experience gathering user needs, translating them to technical inputs, and developing viable V&V (Design Verification and Validation) plans. Experience leading complex product development initiatives from concept through release. Good working knowledge of anatomy and surgical procedures is required. Demonstrated ability to solve difficult technical problems and deliver practical solutions that meet the application requirements is required. This includes strong analytical, problem-solving, and decision-making skills with the ability to be observant and to think creatively. Demonstrated ability to design experiments and analyze data with appropriate quality and statistical methodologies. Demonstrated ability to work independently as well as effectively be a strong team contributor and work cross-functionally to expedite the completion of critical project tasks Ability to handle multiple project assignments of medium scope and complexity and able to prioritize and complete work with a sense of urgency in a timely manner. Ability to lead directly and by influence, including strong problem-solving, conflict resolution, and analytical skills. Requires strong leadership skills, excellent written and verbal communication and presentation skills. Working knowledge of FDA requirements as per 21 CFR 820 Proficiency in the use of Microsoft Excel, Microsoft Word, and Microsoft PowerPoint is required. Legal authorization to work in the United States is required. Preferred Qualifications An advanced degree (MS or Ph.D.) is highly preferred. Hands-on experience in product development with Class II and Class III medical devices. Experience developing test methods and protocols/reports for safety and efficacy testing of implant and instrument designs. Working knowledge of ISO 9001, ISO 13485:2003, and ISO 14971:2007. Experience with IDE and PMA submissions. Working knowledge of Good Documentation Practices (GDP), and Good Manufacturing Practices (cGMP) Good understanding of statistical tools and validation/verification techniques. Six-Sigma green belt or black belt certification Cresilon is an equal-opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship. Cresilon makes hiring decisions based solely on qualifications, merit, and business needs at the time. Benefits Competitive annual base salary range of $80,000 - $160,000, depending upon job level and qualifications Paid Vacation, Sick, & Holidays Monthly MetroCard Reimbursement 401(k) & Roth Retirement Savings Plan with company match up to 5% Work/Life Employee Assistance Program Company Paid Life and Short-Term Disability Coverage Medical, Dental, and Vision Insurance, FSA: Dependent & Healthcare, Commuter & Parking Benefits, Long Term Disability Coverage