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ICON is conducting a clinical research study at our facility in Lenexa, KS. We’re seeking: • Healthy, non-smoking men • 18-60 years old • Available for 1 stay of 7 nights and 1 follow-up phone call Qualified study participants may receive compensation up to $5,150 for time and travel. Even if you don’t qualify, you could receive up to $500 for referring a qualified participant. Please note: You will be required to travel to Lenexa, KS, to participate in this study. Click “Reply” to call us now or email us your phone number so we can reach out to you.

Is your current COPD treatment plan not working for you? If you're not currently being treated with an inhaled corticosteroid (ICS), consider seeing if you qualify for our clinical study. Participants can receive compensation for their time. Call our team to see if you qualify (855)367-8834 Refer a Friend and Receive $100 per Qualified Referral

Location: Eatontown, NJ, New York City, NY Age Range: 18-59 Sex: Male, Female Stipend: Up to $6,000 plus travel Study Schedule: Screening Period followed by Outpatient Study Visits, including up to 5 Screening Visits, 24 Study Visits, and 6 Laboratory Sessions. Total participation up to 42 weeks total. Are you between the ages of 18 and 59 and currently physically dependent on opioids? Clinilabs is looking for participants to take part in a research study of an investigational vaccine for the treatment of opioid use disorder (OUD) in adults. There is no cost to participate. Those who qualify will receive up to $6,000 in compensation for time and participation. We encourage you to review the participation requirements below. To qualify, participants must meet the following criteria (additional criteria apply): • Current opioid users • Have experience with intranasal opioid use • Between the ages of 18 and 59 • Have a weight less than 300lbs or have a maximum girth of less than 52 inches Be able and willing to: • Attend up to 5 screening visits at Clinilabs location in Eatontown, NJ or Manhattan, NY • If qualified, return for regular outpatient visits at Clinilabs location in Eatontown, NJ • Complete on-site pre-qualification testing including, but not limited to, ECG, urinalysis, and bloodwork Participants may receive compensation up to $6,000 for completing all required study visits and laboratory sessions, plus travel reimbursement. Additional compensation may be provided based on the number of Screening visits completed and the Completion bonus earned. Total compensation is dependent on the number of visits completed. • $75 – Screening visits (up to 5 visits) • $150 – Outpatient study visits (up to 24 visits) • $200 – Laboratory (blood draw) visits (up to 6 visits) • $200 – Completion bonus for completing both laboratory visits each week (up to $400 per week or $1,200 total) • Up to $80 travel reimbursement per on-site visit Know someone struggling with opioid addiction? Refer them to our study and you could receive a $100 gift card as a thank-you. Just make sure they mention your name with the correct spelling when speaking to our recruitment coordinator. For complete study details visit: https://clinilabs.com/volunteer-study/outpatient-opioid-use-disorder/

Location: Eatontown, NJ, New York City, NY Age Range: 18-59 Sex: Male, Female Stipend: Up to $6,000 plus travel Study Schedule: Screening Period followed by Outpatient Study Visits, including up to 5 Screening Visits, 24 Study Visits, and 6 Laboratory Sessions. Total participation up to 42 weeks total. Are you between the ages of 18 and 59 and currently physically dependent on opioids? Clinilabs is looking for participants to take part in a research study of an investigational vaccine for the treatment of opioid use disorder (OUD) in adults. There is no cost to participate. Those who qualify will receive up to $6,000 in compensation for time and participation. We encourage you to review the participation requirements below. To qualify, participants must meet the following criteria (additional criteria apply): • Current opioid users • Have experience with intranasal opioid use • Between the ages of 18 and 59 • Have a weight less than 300lbs or have a maximum girth of less than 52 inches Be able and willing to: • Attend up to 5 screening visits at Clinilabs location in Eatontown, NJ or Manhattan, NY • If qualified, return for regular outpatient visits at Clinilabs location in Eatontown, NJ • Complete on-site pre-qualification testing including, but not limited to, ECG, urinalysis, and bloodwork Participants may receive compensation up to $6,000 for completing all required study visits and laboratory sessions, plus travel reimbursement. Additional compensation may be provided based on the number of Screening visits completed and the Completion bonus earned. Total compensation is dependent on the number of visits completed. • $75 – Screening visits (up to 5 visits) • $150 – Outpatient study visits (up to 24 visits) • $200 – Laboratory (blood draw) visits (up to 6 visits) • $200 – Completion bonus for completing both laboratory visits each week (up to $400 per week or $1,200 total) • Up to $80 travel reimbursement per on-site visit Know someone struggling with opioid addiction? Refer them to our study and you could receive a $100 gift card as a thank-you. Just make sure they mention your name with the correct spelling when speaking to our recruitment coordinator. For complete study details visit: https://clinilabs.com/volunteer-study/outpatient-opioid-use-disorder/

Location: Eatontown, NJ, New York City, NY Age Range: 18-59 Sex: Male, Female Stipend: Up to $6,000 plus travel Study Schedule: Screening Period followed by Outpatient Study Visits, including up to 5 Screening Visits, 24 Study Visits, and 6 Laboratory Sessions. Total participation up to 42 weeks total. Are you between the ages of 18 and 59 and currently physically dependent on opioids? Clinilabs is looking for participants to take part in a research study of an investigational vaccine for the treatment of opioid use disorder (OUD) in adults. There is no cost to participate. Those who qualify will receive up to $6,000 in compensation for time and participation. We encourage you to review the participation requirements below. To qualify, participants must meet the following criteria (additional criteria apply): • Current opioid users • Have experience with intranasal opioid use • Between the ages of 18 and 59 • Have a weight less than 300lbs or have a maximum girth of less than 52 inches Be able and willing to: • Attend up to 5 screening visits at Clinilabs location in Eatontown, NJ or Manhattan, NY • If qualified, return for regular outpatient visits at Clinilabs location in Eatontown, NJ • Complete on-site pre-qualification testing including, but not limited to, ECG, urinalysis, and bloodwork Participants may receive compensation up to $6,000 for completing all required study visits and laboratory sessions, plus travel reimbursement. Additional compensation may be provided based on the number of Screening visits completed and the Completion bonus earned. Total compensation is dependent on the number of visits completed. • $75 – Screening visits (up to 5 visits) • $150 – Outpatient study visits (up to 24 visits) • $200 – Laboratory (blood draw) visits (up to 6 visits) • $200 – Completion bonus for completing both laboratory visits each week (up to $400 per week or $1,200 total) • Up to $80 travel reimbursement per on-site visit Know someone struggling with opioid addiction? Refer them to our study and you could receive a $100 gift card as a thank-you. Just make sure they mention your name with the correct spelling when speaking to our recruitment coordinator. For complete study details visit: https://clinilabs.com/volunteer-study/outpatient-opioid-use-disorder/

Location: Eatontown, NJ, New York City, NY Age Range: 18-59 Sex: Male, Female Stipend: Up to $6,000 plus travel Study Schedule: Screening Period followed by Outpatient Study Visits, including up to 5 Screening Visits, 24 Study Visits, and 6 Laboratory Sessions. Total participation up to 42 weeks total. Are you between the ages of 18 and 59 and currently physically dependent on opioids? Clinilabs is looking for participants to take part in a research study of an investigational vaccine for the treatment of opioid use disorder (OUD) in adults. There is no cost to participate. Those who qualify will receive up to $6,000 in compensation for time and participation. We encourage you to review the participation requirements below. To qualify, participants must meet the following criteria (additional criteria apply): • Current opioid users • Have experience with intranasal opioid use • Between the ages of 18 and 59 • Have a weight less than 300lbs or have a maximum girth of less than 52 inches Be able and willing to: • Attend up to 5 screening visits at Clinilabs location in Eatontown, NJ or Manhattan, NY • If qualified, return for regular outpatient visits at Clinilabs location in Eatontown, NJ • Complete on-site pre-qualification testing including, but not limited to, ECG, urinalysis, and bloodwork Participants may receive compensation up to $6,000 for completing all required study visits and laboratory sessions, plus travel reimbursement. Additional compensation may be provided based on the number of Screening visits completed and the Completion bonus earned. Total compensation is dependent on the number of visits completed. • $75 – Screening visits (up to 5 visits) • $150 – Outpatient study visits (up to 24 visits) • $200 – Laboratory (blood draw) visits (up to 6 visits) • $200 – Completion bonus for completing both laboratory visits each week (up to $400 per week or $1,200 total) • Up to $80 travel reimbursement per on-site visit Know someone struggling with opioid addiction? Refer them to our study and you could receive a $100 gift card as a thank-you. Just make sure they mention your name with the correct spelling when speaking to our recruitment coordinator. For complete study details visit: https://clinilabs.com/volunteer-study/outpatient-opioid-use-disorder/